Methionine - instruction, application, indications. Methionine - instructions, reviews.
Is a substance that is a part of the drug of the same name.
The drug is available in the form of powder, capsules, syrup, coated tablets ( one tablet contains 250 mg of active ingredient).
Synonyms of the name
Atonin, Banthionine, Atinone, Acimethion, Amethionol, Thiomedon, Atinone, Meionine.Healing properties
Methionine is one of the essential amino acids. It is not synthesized in our body, but enters it from the outside. This amino acid is necessary for the production of various proteins.Properties of this substance:
In general, the composition of the product can be considered good with a question mark. The product is approved as a food additive. The questionnaire is a high content of pantothenic acid and pyridoxine, which are in the recommended dose of 3 capsules in the limit of the maximum allowable daily dose. If this is added to the ration, this maximum amount will be exceeded, and then the product will apparently be used with the recommendation of the attending physician. However, if the daily dose is reduced to 2 capsules, the content of cysteine and methionine will be low.
- Accelerates the regeneration of damaged tissues.
- Activates enzymes and sex hormones.
- Normalizes the function liver.
- Improves digestion.
- Improves lipid metabolism ( that is, fats do not linger and are not deposited in the liver).
- Helps to isolate accumulated toxins from the body.
- Positively affects the body at.
- Binds and removes molecules of heavy metals ( lead, cadmium, mercury).
- Prevents occurrence.
- Prevents fragility of bones and elution of calcium ( at the correct dosage).
- Displays ammonia from the urine.
An insufficient amount of methionine can lead to the retention of fluids in the body, and as a consequence - to the internal swelling (dropsy ). With its small amount, the body's ability to resist also decreases.
Surprisingly, the product does not contain biotin. Incorporation of water-soluble silicon would be beneficial. It would also be advisable to include enough calcium and magnesium, and the manufacturer again seems to expect sufficient current consumption from the food. Because of the higher content of pyridoxine, it is recommended that pregnant women, diabetics and people with Parkinson's disease use this product for consultation with their physician.
The product is not enriched with cysteine or its precursor methionine with a key active ingredient. They primarily affect the quality of the skin. The use of this product will be guaranteed in cases where a sufficient number of amino acids are provided by normal nutrition. This requires almost daily consumption of eggs or more meat. Only if this condition is met, the substances contained in this product will be used to stimulate growth and improve the quality of the hair. The effect of amino acids given in 120 mg of fish proteins is insignificant compared to the amount of normal diet.
Methionine amino acid in the composition of different drugs is used to treat such diseases and pathologies:
- Rheumatoid arthritis.
- Osteoarthritis.
- Diabetes.
- Fibrous-cystic.
- Diseases of the liver ( , ).
- Fibromyalgia.
Indications
- Prevention of liver damage; treatment of diseases that are accompanied by congestion of bile in the liver ( due to the fact that its outflow is disturbed, and the hepatic ducts are blocked with stones) - without severe complications.
- Poisoning chemical substances.
- Poisoning with alcohol.
- Atherosclerosis.
- Dystrophies and exhaustion after the transferred diseases.
Contraindications
- Hepatic coma.
- Hepatitis A (without complications).
- Hypersensitivity to the active substance.
Reception during pregnancy
Information on the safety of Methionine for pregnant and lactating women - no.However, it is known that methionine affects the development of the neural tube in the fetus ( they are the rudiments of the nervous system). If in the body the deficit of this substance ( because the essential amino acids themselves are not produced, they come only with food and specialized drugs such as Methionine), the neural tube will not close, and the embryo will have various disorders and defects of the nervous system.
Therefore, it is desirable to fill the lack of this substance with pregnant women, not with medicines, but with the help of a special one containing meat, cottage cheese, milk, chicken eggs, etc.
Side effects
The drug has no pronounced side effects. Some patients may have vomiting due to the fact that the drug has a bitter taste. Therefore, children are prescribed a drug in the form of a syrup.Interaction with other drugs
Parallel application Methionine and Levodopy (antiparkinsonian drug) leads to a decrease in the efficiency of the latter.There are no data on the interaction of the drug with alcoholic beverages.
It makes no sense to include this ingredient in the product. The composition, the product is more focused on improving the processes of skin regeneration. However, even in this case, it is necessary to provide a sufficient supply of amino acids from normal nutrition. However, for the regeneration of the skin, cysteine is not a key active ingredient, and all the necessary amino acids can be obtained from food in the required amount.
Assess the benefits of this product to promote hair growth and improve their quality is difficult, because its effectiveness depends heavily on the composition of the swallowed food. If a sufficient supply of amino acids is provided, a positive effect can be expected. However, if these amino acids are inaccessible, they do not have keratinous hair cells, and the effect is likely to be controversial.
A course of treatment
The duration of therapy is from ten to thirty days. Sometimes doctors prescribe repeating courses of the drug "10 through 10" - that is, after ten days of taking the medicine to take a ten-day break, and then again to repeat the course.Notes
In parallel with the use of the drug, it is desirable to stick to a protein diet. It is also recommended that the drug be combined with Lipocaine
.Lipokain accelerates phospholipid metabolism in the liver and prevents the formation of fat deposits in the liver.
At reception of a high dose of a preparation it is necessary to use in parallel folic acid and AT 12
, AT 6
(especially for athletes and pregnant women). Athletes usually lower the content of certain hormones and fat in the body, and the excess of methionine leads to the fact that the bones become brittle.
In pregnant women, however, the hormonal background changes and there is an increased stress on the musculoskeletal system due to the development of the fetus. In combination with a high dose of the drug, these factors can affect the fragility of the bones of a pregnant woman.
However, the inclusion of this complex in the product is considered useful. The product is registered as a dietary supplement and has a very well balanced ratio of both key and auxiliary active ingredients. A particular drawback is the size of the tablet. This shortage of tablets was solved by scratching the tablet, so that the tablet can be easily divided and swallowed in parts.
In a recommended daily dose, 2 tablets contain: 300 μg of biotin, 12 mg of pantothenic acid, 15 mg of zinc, 30 mg of silica, the equivalent of about 7 mg of silicon. The product does not contain key active ingredients of cysteine, methionine and the active ingredient pyridoxine. Therefore, a positive effect can be expected only if enough feed is provided for all these substances. The advantage would be to provide a sufficient amount of calcium and magnesium to obtain adequate zinc efficiency.
Deficiency of methionine amino acid is more common in vegetarians . Those who eat meat, the body gets enough methionine, and therefore, to use a drug containing this amino acid - it is not necessary. An exception is the prescription of the drug by a doctor for objective reasons.
As in the case of dietary supplements, vitamins and other beneficial substances, it must be remembered that the excess of substances in the body is just as harmful as their deficiency.
Assess the benefits of this product to promote hair growth and improve its quality is difficult, because its effectiveness is strongly dependent on the composition of food intake. Since the effect of pyridoxine is limited by its consumption of food, there is an increased demand for other amino acids, which otherwise could produce the body by itself. Therefore, the food should be rich in meat and eggs. In the case of an unbalanced reception of amino acids, the negative side of high-dosage biotin can be paradoxically manifested.
Biotin stimulates the transformation of carbohydrates into fatty acids. Generally speaking, from swallowed sugars and starches stimulates an excess of biotin to produce fat, and then stores it in adipose tissue. However, the problem is a high content of pantothenic acid and zinc. Therefore, this method of use should first consult with your doctor. Social Social Faculty of the University of South Bohemia.
Read the official instructions for use Methionine in the abbreviated version. It includes: composition, action, contraindications and indications for use, analogues and reviews. The text is provided for reference only and can not be used as a substitute for a doctor's consultation.
Methionine is an indispensable amino acid necessary for the assimilation, transport and bioaccumulation of zinc and selenium in the body. Methionine also facilitates the breakdown of fats and prevents their accumulation in the liver and arteries.
The health hazards caused by the toxicity of the compounds are often not detected by humans. Paracetamol Acetaminophen is synonymous with paracetamol. Contraindications The most common contraindications are allergy to paracetamol and acute hepatitis. Interactions When using paracetamol, certain health-hazardous interactions should be avoided. It is necessary to warn that such a situation can come to us after a few days of yelling. People most often risk drinking alcohol, especially when they replace the usual amount of alcohol with paracetamol in case of illness.
Composition and form of the preparation Methionine
Tablets covered with a coating of 0.25 g. 10, 25, 50 tablets per contour cell packaging made of polyvinylchloride film and aluminum foil printed lacquered. For 10, 20, 30, 40, 50 or 100 tablets into a polymer container for medicines or a glass-mass vial with a screw neck with screw caps.
Their cans have a high level of enzymes that process both alcohol and paracetamol, and contain a small amount necessary to remove the toxic paracetamol based intermediate. If a person ceases to consume alcohol and starts using paracetamol, all liver enzymes concentrate on the formation of toxins.
Pharmacokinetics Acetaminophen is a metabolite of acetanilide, benoryl and phenacetin. It is very well absorbed by the tract and quickly distributed to the body fluids. It is metabolized in jars based on hydroxylation, deacetylation and conjugation with cysteine and glucuronic acid. Biotransformation of paracetamol is collected in three ways. The first leads to conjugation with the formation of glucuronide, the second leads to the formation of paracetamol sulfate. This product is directly responsible for both necrosis of the liver and for necrosis of the renal tubules.
One container (vial) or 1, 2, 3, 4, 5, 6, 8, 8 or 10 contiguous cell packs, together with the instruction for use, is placed in a pack of cardboard. 5.10 or 20 containers (bottles) or 20, 40, 60, 80 and 100 contour cell packs, together with the appropriate number of instructions for use, are put in a cardboard box (for hospitals).
Typical doses. Biological half-life. In adults, the biological half-life is 1, 5-3 hours, but the data are 1-4 hours, and the newborn - about 5 hours. Therefore, paracetamol is administered at least. with an interval of 4 hours. In adults more than 4 hours this indicates the ability of liver transplantation. If the dose of paracetamol is high or when the situation changes, Glutathione binding capacity may be exhausted using glutathione. The metabolite then covalently affects the hepatocytes and causes hepatotoxicity, which can lead to death.
The composition of
- Active substance: methionine - 0.25 g.
- Excipients (core): potato starch, methylcellulose, microcrystalline cellulose, stearic acid.
- Sheath: hydroxypropylmethylcellulose, titanium dioxide, acidic red, tween-80
Instructions for the use of methionine
Daily therapeutic dose of methionine
Consequences of abnormal concentrations Project 1: at the stage of intoxication there is an acute gastrointestinal disorder - anorexia, nausea, vomiting, wheezing, temperature, mucous membranes. Phases 2: The phase is associated with a relatively good condition without anorexia and vomiting, lasting about 2 days, usually with oliguria. Phases 3: between day, deafness, fulminant hepatic insufficiency, hemorrhage, hepatic encephalopathy. The glutathione content in the hepatic cells is the limiting in the prediction.
Hepatotoxicity is potentiated with phenobarbitone, whereas glutathione has a protective effect. Hepatic insufficiency of more than 15 g can lead to fatal outcomes even with timely treatment. Later complications may lead to the spread of intravascular coagulation syndrome. The probability of necrosis of liver cells at different time intervals from poisoning by toxic dosing. Within 4 hours after poisoning, the prognosis is unreliable because of the continued absorption of the lysate. More than 15 hours after vaccination late for therapeutic treatment.
Not installed. However, in one study in which methionine supplements were used to treat urinary tract infections, it was found that a dose of 500 mg taken three times a day had a therapeutic effect.
Symptoms of Methionine Deficiency
Lack of methionine can cause apathy, loss of hair pigmentation, swelling, lethargy, liver damage, loss of muscle mass, fat loss, skin damage, weakness and slow growth in children.
Laboratory diagnosis of intoxication The first test is planned approximately 6 hours after sex, and the next - in 3-4 hours. With caution, you should not worry about pregnant women. The introduction of acetylcysteine and methionine should be started within the first 12 hours.
Methionine - 2, 5 g orally, an additional 2, 5 g every 4 hours, it is recommended to monitor blood levels. In the case of a large poison, the patient may experience nausea or vomiting. Acetaminophen is well absorbed into activated charcoal. Some products containing paracetamol.
The maximum safe content of methionine
Not installed.
Indications, contraindications, side effects from the use of methionine
Indications for the use of methionine
Methionine prevents bacteria from sticking to the walls of the bladder; this property of methionine has led to the fact that it is offered as a remedy for recurrent urinary tract infections. In one experiment, evidence was found to confirm this; However, the use of methionine to prevent these diseases is not approved.
Some combination products containing paracetamol. The pharmaceutical industry produces tons of chemicals that can not often be observed. Then we can find that instead of anesthetizing a headache, we need to establish the right diet, clean the device or compare the psyche. Additives: silicon dioxide, magnesium stearate, gelatin, titanium dioxide.
Adults take 1 capsule 2 times a day with a sufficient amount of liquid. The product is not used for any known hypersensitivity to any of the ingredients. The product is not suitable for children, pregnant and lactating women and people with edema of the kidney and heart origin. The product is not intended to be used as a substitute for a varied diet. It does not have approved medicinal effects and is not a medicine.
It turned out that methionine is effective in preventing poisoning with acetaminophen, and some experts suggest selling acetaminophen in combination with this amino acid to prevent poisoning. However, there are a number of assumptions that the continued use of methionine can lead to an increase in the level of homocysteine.
Does the gene correctly handle folic acid in your body?
Food supplements are not intended to replace a varied diet. Are you planning a pregnancy and are wondering what to do to make things right? Want to prevent the most dangerous problems that can arise during pregnancy? Folic alkaloids are the key substances necessary for proper preparation for pregnancy. Because folate metabolism can occur in different organisms in different ways, it is very important to choose the right form for them. Learn more about folate and folate and read about the addition.
Side effects and contraindications of the amino acid methionine
Some studies show that methionine helps to alleviate some of the symptoms of Parkinson's disease. Experiments on animals suggest that high doses of methionine in conditions of vitamin B deficiency can increase the risk of atherosclerosis, raising the level of cholesterol and homocysteine in the blood.
Are you in a group of women who are at an increased risk of miscarriage?
Folic acid is necessary for this process. This causes homocysteine to accumulate in the body, contributing to inflammation, which can lead, in particular. Problems with pregnancy. Simply put, if the gene does not work properly, the addition of folic acid will not lead to the expected result, which can lead to miscarriage or developmental defects.
Do you have an increased risk of depression?
Because sometimes a deficiency of folic acid is a malfunction. It is dictated that folic acid affects the regulation of the level of homocysteine from which methionine is produced, which, in turn, produces serotonin and norepinephrine - hormones of happiness!
- People taking methionine supplements should make sure that they receive the recommended doses of folic acid, vitamin B6 and vitamin B12.
- People with liver or kidney disease should consult their physician before taking methionine supplements.
Methionine enters the body with food: from brewer's yeast, dairy products, eggs, fish, meat, seafood and whey.
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